Characters: Lady Macduff, her son, Rosse, a messenger, Murderers
Location: Fife. A room in Macduff’s castle.
Events: Lady Macduff tells Rosse that her husband’s flight to England showed little concern for his family and questions why he has gone. When Rosse leaves, Lady Macduff’s son, who refuses to believe that his father is dead, asks about traitors. A messenger arrives and warns Lady Macduff of approaching danger. The Murderers burst in, kill Macduff’s son and attempt to kill his fleeing mother.